Marvel Stadium · Sat 27 Mar 2021, 7:25pm AEDT
Melbourne beat St Kilda 12.19 (91) to 11.7 (73) in the 2021 Round 2 at Marvel Stadium on Sat 27 Mar 2021.
Updated Sat 25 Sep 2021, 10:28pm (Melbourne time)
| Competition | AFL 2021, Round 2 |
| Venue | Marvel Stadium |
| Bounce | Sat 27 Mar 2021, 7:25pm AEDT |
| St Kilda | 11.7 (73) |
| Melbourne | 12.19 (91) |
| Result | Melbourne by 18 points |