All 4 games of Round 16, 1921 are complete. The biggest win was Richmond over Essendon by 35 points; the closest was Melbourne over Fitzroy by 1.
Updated Mon 21 Nov 2022, 4:27pm (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Essendon | 5.15 (45) | Richmond | 11.14 (80) | East Melbourne |
| Geelong | 6.11 (47) | Carlton | 8.15 (63) | Corio Oval |
| St Kilda | 10.7 (67) | Collingwood | 12.7 (79) | Junction Oval |
| Fitzroy | 9.8 (62) | Melbourne | 9.9 (63) | Brunswick St |