All 9 games of Round 21, 2022 are complete. The biggest win was Geelong over St Kilda by 45 points; the closest was Collingwood over Melbourne by 7.
Updated Sat 24 Sep 2022, 5:40pm (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Melbourne | 13.11 (89) | Collingwood | 15.6 (96) | MCG |
| Hawthorn | 10.10 (70) | Gold Coast | 8.15 (63) | York Park |
| Greater Western Sydney | 14.12 (96) | Essendon | 10.9 (69) | ENGIE Stadium |
| Western Bulldogs | 11.12 (78) | Fremantle | 14.11 (95) | Marvel Stadium |
| Geelong | 17.8 (110) | St Kilda | 10.5 (65) | GMHBA Stadium |
| Port Adelaide | 10.11 (71) | Richmond | 16.13 (109) | Adelaide Oval |
| North Melbourne | 13.10 (88) | Sydney | 18.18 (126) | Marvel Stadium |
| Brisbane Lions | 17.12 (114) | Carlton | 12.9 (81) | Gabba |
| West Coast | 13.8 (86) | Adelaide | 16.6 (102) | Optus Stadium |