All 6 games of Round 16, 1981 are complete. The biggest win was Essendon over Western Bulldogs by 93 points; the closest was Collingwood over Carlton by 1.
Updated Thu 17 Nov 2022, 9:54am (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Collingwood | 11.11 (77) | Carlton | 10.16 (76) | Victoria Park |
| Essendon | 22.21 (153) | Western Bulldogs | 8.12 (60) | Windy Hill |
| Hawthorn | 12.14 (86) | Richmond | 20.11 (131) | Princes Park |
| Melbourne | 12.7 (79) | Geelong | 22.35 (167) | MCG |
| Sydney | 22.19 (151) | St Kilda | 16.4 (100) | Lake Oval |
| Fitzroy | 18.13 (121) | North Melbourne | 12.15 (87) | Waverley Park |