All 6 games of Round 4, 1981 are complete. The biggest win was Fitzroy over Sydney by 69 points; the closest was Collingwood over Geelong by 8.
Updated Thu 17 Nov 2022, 9:54am (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Melbourne | 10.16 (76) | St Kilda | 16.32 (128) | MCG |
| North Melbourne | 13.17 (95) | Richmond | 17.22 (124) | Waverley Park |
| Fitzroy | 25.19 (169) | Sydney | 14.16 (100) | Junction Oval |
| Essendon | 11.13 (79) | Hawthorn | 13.16 (94) | Windy Hill |
| Geelong | 9.14 (68) | Collingwood | 11.10 (76) | GMHBA Stadium |
| Western Bulldogs | 11.10 (76) | Carlton | 15.14 (104) | Waverley Park |