All 6 games of Round 21, 1981 are complete. The biggest win was Essendon over Sydney by 111 points; the closest was Richmond over Melbourne by 17.
Updated Thu 17 Nov 2022, 9:54am (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Collingwood | 22.17 (149) | Hawthorn | 11.10 (76) | Victoria Park |
| Essendon | 26.23 (179) | Sydney | 10.8 (68) | Windy Hill |
| Geelong | 18.20 (128) | Western Bulldogs | 8.11 (59) | GMHBA Stadium |
| Melbourne | 15.9 (99) | Richmond | 17.14 (116) | MCG |
| North Melbourne | 8.14 (62) | Carlton | 12.12 (84) | Waverley Park |
| Fitzroy | 14.18 (102) | St Kilda | 9.10 (64) | Junction Oval |