All 6 games of Round 12, 2021 are complete. The biggest win was Richmond over Essendon by 39 points; the closest was Collingwood over Adelaide by 5.
Updated Sat 25 Sep 2021, 10:28pm (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Melbourne | 14.13 (97) | Brisbane Lions | 11.9 (75) | ENGIE Stadium |
| Sydney | 13.14 (92) | St Kilda | 12.11 (83) | SCG |
| Adelaide | 10.13 (73) | Collingwood | 12.6 (78) | Adelaide Oval |
| Essendon | 12.12 (84) | Richmond | 19.9 (123) | Optus Stadium |
| Carlton | 10.13 (73) | West Coast | 14.11 (95) | SCG |
| Fremantle | 9.11 (65) | Western Bulldogs | 13.15 (93) | Optus Stadium |