All 9 games of Round 16, 2021 are complete. The biggest win was Sydney over West Coast by 92 points; the closest was Greater Western Sydney over Melbourne by 9.
Updated Sat 25 Sep 2021, 10:28pm (Melbourne time)
| Home | Score | Away | Score | Venue |
|---|---|---|---|---|
| Gold Coast | 10.17 (77) | Richmond | 10.7 (67) | Marvel Stadium |
| Geelong | 15.8 (98) | Essendon | 8.9 (57) | GMHBA Stadium |
| Melbourne | 7.13 (55) | Greater Western Sydney | 9.10 (64) | MCG |
| Adelaide | 8.11 (59) | Brisbane Lions | 17.9 (111) | Adelaide Oval |
| Fremantle | 8.16 (64) | Carlton | 12.8 (80) | MCG |
| Hawthorn | 7.11 (53) | Port Adelaide | 13.9 (87) | Marvel Stadium |
| Sydney | 18.10 (118) | West Coast | 3.8 (26) | GMHBA Stadium |
| Collingwood | 8.13 (61) | St Kilda | 10.10 (70) | MCG |
| Western Bulldogs | 16.12 (108) | North Melbourne | 11.13 (79) | Marvel Stadium |